What Are The Causes of Acquired Hyper-pigmentation?

The causes of acquired hyper pigmentation can roughly be broken up into endogenous and environmental causes.

Endogenous causes include:

Solar lentigines

Melasma

Scars

Ephelides

Other rare systemic skin diseases

Hemochromotosis (iron pigment)

Renal Failure

Liver Disease

Pituitary tumors

Pregnancy

Chronic stress

Environmental causes are:

Ultra-violet irradiation (e.g. Sunlight, tanning beds)

Photo-sensitizing agents

Cosmetics

Pharmaceuticals (estrogen, antibiotics, phyenyltoin, phenothiazines)

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